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JEE Main 2021
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Animated Solution for Chemistry - Organic Chemistry: Deficiency of vitamin K causes

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Visualized Solution

  • Vitamin K is an essential fat-soluble vitamin that plays a critical role in blood coagulation.
  • It is required for the synthesis of certain proteins (clotting factors) in the liver that help the blood to clot.

  • A deficiency in Vitamin K means the blood lacks these essential clotting factors.
  • Without sufficient clotting factors, the coagulation process is delayed, leading to an increased time for the blood to clot.

  • Therefore, deficiency of Vitamin K causes an increase in blood clotting time.

The Sigma Insight: Biomolecules

The Crucial Role of Vitamin K

Have you ever wondered how a simple paper cut stops bleeding after a few minutes? It is not magic; it is a highly complex biological cascade happening right inside your blood vessels. At the heart of this life-saving mechanism is a vital nutrient: Vitamin K.
Vitamin K is a fat-soluble vitamin that acts as a coenzyme for the synthesis of proteins involved in blood coagulation (clotting) and bone metabolism. The 'K' actually comes from the German word Koagulationsvitamin.

What Happens When Vitamin K is Deficient?

When your body lacks Vitamin K, the liver cannot produce enough of the essential clotting factors (like prothrombin). Imagine trying to build a brick wall without enough cement. The bricks might be there, but they won't hold together quickly or strongly.
Similarly, without sufficient Vitamin K, the blood's ability to coagulate is severely compromised. This means that if an injury occurs, the bleeding will continue for a much longer duration than normal. In medical terms, we say that the blood clotting time is increased.

Analyzing the Options

Let's look at the other options provided in the question to understand why they are incorrect:
Increase in fragility of RBC's: This is typically caused by a deficiency in Vitamin E, which acts as an antioxidant protecting cell membranes. Cheilosis: This condition, characterized by cracking at the corners of the mouth, is a classic symptom of Vitamin B2 (Riboflavin) deficiency. Decrease in blood clotting time: This would mean the blood clots faster* than normal, which is the exact opposite of what happens when you lack the necessary clotting factors.
Therefore, the correct and logical consequence of Vitamin K deficiency is an increase in blood clotting time.

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